Publications

Group highlights

(For a full list see below or go to Google Scholar)

Full List

Microbial cancer immunotherapy reprograms hematopoiesis to enhance anti-tumor immunity
Andrew W. Daman, Anthony Claude Antonelli, Gil Redelman-Sidi, et al.
bioRxiv. 2024

The potency of hematopoietic stem cell reprogramming for changing immune tone
Andrew W. Daman, Jin-Gyu Cheong, Laura Berneking, Steven Z. Josefowicz
Immunol Rev. 2024

Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection
Alexander Lercher, Jin-Gyu Cheong, Chenyang Jiang, et al.
bioRxiv. 2023

Epigenetic memory of coronavirus infection in innate immune cells and their progenitors
Jin-Gyu Cheong, Arjun Ravishankar, Siddhartha Sharma, et al.
Cell. 2023

Epigenetic and transcriptional control of interferon-β
Andrew W. Daman, Steven Z. Josefowicz
J Exp Med. 2021

Signaling-to-chromatin pathways in the immune system
Alexia Martinez de Paz, Steven Zvi Josefowicz
Immunol Rev. 2021

A histone code for inducible transcription in immune responses
Alexia Martinez de Paz, Wendy Beguelin, Merve Sahin et al.
J Immunol. 2020

Histone H3.3 phosphorylation amplifies stimulation-induced transcription
Anja Armache* et al.
Nat. 2020

Gene regulatory networks STARR-ing B cells
Alexia Martinez de Paz, Steven Zvi Josefowicz
Nat Imm. 2019

Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription
Josefowicz SZ*, Shimada M, Armache A, Li CH, Miller RM, Lin S, Yang A, Dill BD, Molina H, Park H-S et al.
Mol Cell. 64(2):347-361. 2016

Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.
Soshnev AA, Josefowicz SZ*, C Allis D.
Mol Cell. 62(5):681-94. 2016

Regulators of chromatin state and transcription in CD4 T-cell polarization
Josefowicz SZ*.
Immunology. 139(3):299-308. 2013

Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict
Samstein RM, Josefowicz SZ, Arvey A, Treuting PM, Rudensky AY.
Cell. 150(1):29-38. 2012

Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification.
Samstein RM, Arvey A, Josefowicz SZ, Peng X, Reynolds A, Sandstrom R, Neph S, Sabo P, Kim JM, Liao W et al.
Cell. 151(1):153-66. 2012

Extrathymically generated regulatory T cells control mucosal TH2 inflammation.
Josefowicz SZ*, Niec RE, Kim HY, Treuting P, Chinen T, Zheng Y, Umetsu DT, Rudensky AY.
Nature. 482(7385):395-9. 2012

Regulatory T cells: mechanisms of differentiation and function.
Josefowicz SZ*, Lu L-F, Rudensky AY.
Annu Rev Immunol. 30:531-64. 2012.

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate.
Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY.
Nature. 463(7282):808-12. 2010

Control of regulatory T cell lineage commitment and maintenance.
Josefowicz SZ, Rudensky A.
Immunity. 30(5):616-25. 2009

Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1.
Josefowicz SZ, Wilson CB, Rudensky AY.
J Immunol. 182(11):6648-52. 2009

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.
Zheng Y, Josefowicz SZ, Kas A, Chu T-T, Gavin MA, Rudensky AY.
Nature. 445(7130):936-40. 2007